Biochemistry MCQs

1.Which of the following pairings is accurate?

Thiamine – Acyl CoABiotin – Carbon DioxideATP – HydrogenAll of these

2.Which of the following metabolic processes is NOT stimulated by insulin in the liver?

Synthesis of fatty acidsFormation of glycogenProtein productionGeneration of glucose

3.Which of the following sugars has the highest tendency to promote fat synthesis?

FructoseGlucoseGalactoseRibose

4.Which enzyme deficiency is responsible for Type II glycogen storage disease?

Alpha-glucosidaseAlpha-galactosidaseMuscle phosphorylaseAcid lipase

5.Which of the following is the primary component found in dietary fiber?

6.Fructose intolerance primarily affects the metabolism of which substances?

7.Which of the following statements accurately describes the monosaccharide glucose?

Glucose primarily adopts the furanose ring structure.Glucose is classified as a ketose sugar.Glucose contains an anomeric carbon at position 2.Glucose is a constituent sugar in the disaccharide sucrose.Glucose is a polysaccharide made of multiple sugar units.

8.How many ATP molecules are produced during the conversion of glycogen to lactate?

9.Which enzyme is responsible for producing NADPH?

Glucose-6-phosphate dehydrogenaseGlucose-1-phosphate dehydrogenaseGlucose-1,6-bisphosphate dehydrogenaseAll the enzymes listed above

10.Why is the HMP shunt crucial in cellular metabolism?

11.In which condition is a deficiency of glucose-6-phosphatase observed?

Pompe's diseaseVon Gierke's diseaseMcArdle's syndromeDown syndrome

12.Which of the following locations are known sites where HMP shunts may take place?

13.Which stage of the Hexose Monophosphate (HMP) pathway depends on thiamine pyrophosphate (TPP)?

14.How many pyruvate molecules are produced from one molecule of glucose during glycolysis?

15.Which metabolic pathways primarily operate in the brain?

Glycolysis and the citric acid cycleGlycogen breakdown and glucose synthesisEmbden-Meyerhof pathway and the hexose monophosphate shuntGlycogen breakdown and the citric acid cycleNone of the above

16.During glycolysis, which enzyme is responsible for generating ATP?

17.What term describes the suppression of glycolysis in the presence of oxygen?

18.What is the correct sequence in which the following Krebs cycle intermediates appear after acetyl CoA enters the cycle?

Citrate, Oxaloacetate, Alpha-ketoglutarateAlpha-ketoglutarate, Oxaloacetate, CitrateCitrate, Alpha-ketoglutarate, OxaloacetateOxaloacetate, Alpha-ketoglutarate, Citrate

19.In which of the following does the Krebs cycle fail to take place?

20.During the tricarboxylic acid (TCA) cycle, which compound is produced initially?

Isocitric acidCitric acidSuccinateFumaric acid