Which anxiolytic medication, used to treat generalized anxiety, does not act on the GABAergic system?

Pharmacology MCQs for PPSC, FPSC, NTS, and Pakistan government job tests. Select an option below, then read the explanation.

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Subject
Pharmacologymedical-mcqs › pharmacology
Published
30 Jul 2019
Last updated
28 May 2026

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Explanation

Alprazolam, Diazepam, and Phenobarbital all exert their anxiolytic effects by enhancing the GABAergic system. In contrast, Buspirone is an anxiolytic that works through serotonin receptors and does not interact with the GABAergic pathway, making it distinct in its mechanism of action.

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