What triggers the activation of pepsinogen?

Physiology Mcqs for PPSC, FPSC, NTS, and Pakistan government job tests. Select an option below, then read the explanation.

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Subject
Physiology Mcqsmedical-mcqs › physiology-mcqs
Published
13 Jul 2019
Last updated
28 May 2026

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Explanation

Pepsinogen, an inactive enzyme precursor, is converted into its active form, pepsin, by exposure to a low pH (acidic conditions) in the stomach. This acidic environment induces the structural change necessary for activation. Other enzymes like enterokinase, trypsin, and chymotrypsin do not activate pepsinogen.

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