What is the accurate cytogenetic notation for Down syndrome caused by a translocation between chromosome 14 and chromosome 21?

Pathology MCQs for PPSC, FPSC, NTS, and Pakistan government job tests. Select an option below, then read the explanation.

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Subject
Pathologymedical-mcqs › pathology
Published
27 Jul 2019
Last updated
28 May 2026

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Explanation

Option D correctly represents the karyotype for Down syndrome due to a translocation between chromosomes 14 and 21, showing an extra chromosome resulting from this rearrangement. The other options either indicate incorrect chromosome numbers or missing chromosomes, which do not correspond to the translocation form of Down syndrome.

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