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Pathology

Free 321+ Pathology MCQs for PPSC, FPSC, NTS, and Pakistan government job tests. Practise below with answers and explanations.

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Pathology — MCQs for Pakistan government job tests

About this subject

Pathology Mcqs for preparation. These Mcqs are helpful for Medical students. Pathology Multiple Choice Questions (MCQ) for entrance examinations and other competitive examinations for all Experienced, Freshers and Students.

Subcategories

Explore narrower topics under Pathology with their own MCQ sets.

Cell In Health And Disease

Diseases of Blood And Lymphnodes

Fluid And Heamodynamic Disorders

Growth Disorders And Neoplasia

Healing

Inflammation, Immunity And Hypersensitivity

Systemic Pathology & Miscellaneous

Cell In Health And Disease
Diseases of Blood And Lymphnodes
Fluid And Heamodynamic Disorders
Growth Disorders And Neoplasia
Healing
Inflammation, Immunity And Hypersensitivity
Systemic Pathology & Miscellaneous

Practice questions

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1.Which of the following statements about nuclear changes during cell death is accurate?

Pyknosis refers to the condensation and shrinkage of the nucleus.Karyolysis is the process of nuclear dissolution.Karyorrhexis involves the breaking apart of the nucleus.All of the above are correct.

2.Which of the following statements is accurate?

Low-density lipoproteins are primarily linked to the development of atherosclerosis.High-density lipoproteins play a protective role against atherosclerosis.Polyunsaturated fats help reduce cholesterol levels in the blood.HDL particles carry the greatest amount of cholesterol.

3.Which of the following statements about thrombi is accurate?

Arterial thrombi lead to ischemia and infarction, while cardiac and venous thrombi typically result in embolism.Arterial thrombi tend to be white and non-occlusive (mural), whereas venous thrombi are red and occlusive.Venous thrombi are soft, red, and gelatinous, in contrast to arterial thrombi which are firm and white.All of the above statements are correct.None of the above statements are true.

4.Which of the following statements about cervicofacial actinomycosis is INCORRECT?

110-20% of actinomycosis infections are located in the cervicofacial areaPus discharge typically contains visible sulfur granulesBlood agar cultures often show a characteristic molar tooth appearanceA history of trauma, such as dental extraction or jaw injury, is commonly present

5.Where are mural thrombi typically located?

Inside the chambers of the heartOn the leaflets of heart valvesWithin veinsIn the arteries

6.Which disease does carrying one sickle cell gene (heterozygous sickle cell trait) provide resistance against?

Glucose-6-phosphate dehydrogenase deficiencyMalariaThalassemiaDengue fever

7.What is the accurate cytogenetic notation for Down syndrome caused by a translocation between chromosome 14 and chromosome 21?

47, X &, +247, XY, missing chromosome 14 with translocation between 14 and 2146, XY, deletion of chromosome 14 with translocation between 14 and 2147, XY, with translocation t(14;21)

8.Which form of immune response is primarily triggered by T-helper 2 (TH2) cells?

Promotes cell-mediated immune defenseStimulates antibody-mediated immunityActivates cytotoxic T lymphocyte responseDoes not initiate any immune response

9.What is the typical amount of iron lost daily by a healthy adult male?

0.06 milligrams0.6 milligrams60 milligrams600 milligramsNone of the above

10.Which congenital defect is associated with mutations in the HOX gene?

PolysyndactylyHoloprosencephalyMayer-Rokitansky-Küster-Hauser syndromeGorlin syndromeNone of the above

11.Fibrin degradation products are primarily used to diagnose which condition?

HemophiliaDisseminated Intravascular Coagulation (DIC)Thrombocytopenic PurpuraThrombasthenia

12.Which syndrome is identified by the presence of two X chromosomes and one Y chromosome?

Klinefelter syndromeDown syndromeTurner syndromeMarfan syndrome

13.What is the primary cause of pulmonary embolism?

ThrombophlebitisEndarteritisAtherosclerosisLymphangitis

14.A newborn presents with cleft lip and palate, extra fingers (polydactyly), a small head (microcephaly) accompanied by holoprosencephaly, and an ectodermal defect on the scalp. Which chromosomal abnormality is most likely responsible for these findings?

Down syndrome (Trisomy 21)Edwards syndrome (Trisomy 18)Patau syndrome (Trisomy 13)Turner syndrome (Monosomy X)Cri-du-chat syndrome

20.A patient exhibits an elevated count of columnar epithelial cells in the distal esophagus. What type of tissue alteration does this represent?

Abnormal cellular developmentLoss of cellular differentiationReplacement of one mature cell type with anotherTypical tissue structureNo change observed

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How to prepare with Pathology MCQs

Work through questions topic by topic, then revisit any you answered incorrectly.
Read explanations carefully—they often cover facts that repeat across PPSC, FPSC, and NTS papers.
Pair subject practice with past papers to see how Pathology appears in real exam conditions.