Which statement is true regarding a drug that follows first-order elimination kinetics?

Pharmaceutical Chemistry Mcqs for PPSC, FPSC, NTS, and Pakistan government job tests. Select an option below, then read the explanation.

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Published
5 Apr 2022
Last updated
28 May 2026

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Choose the correct answer

Explanation

In first-order kinetics, the clearance of the drug remains constant regardless of concentration, meaning the rate of elimination is proportional to the drug amount present. Therefore, clearance does not change with dose. Options A and C are incorrect because the amount eliminated per time varies and half-life does not increase with dose in first-order kinetics. Option D is incomplete and misleading.

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